Circulation2022Open AccessHighly Cited

Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression

E. Born, Larissa Lipskaia, Marielle Breau et al.

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Original research published by Born et al. in Circulation. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.

Abstract

Elimination of senescent P-ECs by senolytic interventions may worsen pulmonary hemodynamics. These results invite consideration of the potential impact on pulmonary vessels of strategies aimed at controlling cell senescence in various contexts.

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Article Details
DOI10.1161/circulationaha.122.058794
JournalCirculation
Year2022
AuthorsE. Born, Larissa Lipskaia, Marielle Breau, Amal Houssaïni, Delphine Beaulieu, Élisabeth Marcos, Rémi Pierre, Marcio Do Cruzeiro, Marine Lefèvre, Geneviève Dérumeaux, Dmitry V. Bulavin, Marion Delcroix, Rozenn Quarck, Virinder Reen, Jesús Gil, David Bernard, Jean‐Michel Flaman, Serge Adnot, Shariq Abid
LicenseOpen Access — see publisher for license terms
Citations126