Evolving Global Etiology of Hepatocellular Carcinoma (HCC): Insights and Trends for 2024
Abraham Koshy
Research Article — Peer-Reviewed Source
Original research published by Koshy et al. in Journal of Clinical and Experimental Hepatology. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.
Abstract
The epidemiology of HCC is changing all over the world and the incidence of HCC is expected to continue increasing over the next 30 years. The changes are in the predisposing factors. Hepatitis B and hepatitis C as predisposing etiologies are decreasing while NAFLD/MAFLD is increasing. The increase in MAFLD is so great that despite the decrease in hepatitis B and C, the overall incidence of HCC is increasing. HCC in persons below the age of 20 years has distinct characteristics different from that of HCC in adults. The changing etiology of hepatocellular carcinoma has implications for the early detection, prevention, the stage of HCC at time of detection and in the treatment of HCC. The extent of these changes and their significance are discussed.
| DOI | 10.1016/j.jceh.2024.102406 |
| PubMed ID | 39346785 |
| PMC ID | PMC11426038 |
| Journal | Journal of Clinical and Experimental Hepatology |
| Year | 2024 |
| Authors | Abraham Koshy |
| License | Open Access — see publisher for license terms |
| Citations | 85 |