Identification of peptide and protein doping related drug compounds confiscated in Denmark between 2007-2013
Rune A. Hartvig, Niels Bjerre Holm, Petur Weihe Dalsgaard et al.
Research Article — Peer-Reviewed Source
Original research published by Hartvig et al. in Scandinavian Journal of Forensic Science. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.
Abstract We present an overview of protein and peptide compounds confiscated in Denmark from late 2007 till late 2013 together with a description of a newly developed HRAM-LC-MS method used for identification. As examples of identification, we present data for the peptides AOD-9604, [D-Ala 2 , Gln 8 , Ala 15 , Leu 27 ]sermorelin and the protein follistatin. It was found that a method with minimum sample preparation could be implemented for all of the confiscated peptides and the protein somatropin. However, for the protein follistatin it was necessary to include trypsin digestion in the sample preparation, which considerably increases the overall analysis time.
Full text is available at the publisher.
Read at Publisher| DOI | 10.2478/sjfs-2014-0003 |
| Journal | Scandinavian Journal of Forensic Science |
| Year | 2014 |
| Authors | Rune A. Hartvig, Niels Bjerre Holm, Petur Weihe Dalsgaard, Lotte Ask Reitzel, Irene Müller, Kristían Línnet |
| License | Open Access — see publisher for license terms |
| Citations | 12 |