Analytical and Bioanalytical Chemistry2008Open AccessHighly Cited

Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey

Geertruida A. Posthuma‐Trumpie, Jakob Korf, A. van Amerongen

1,506 citations2008Open Access — see publisher for license terms1 related compound

Research Article — Peer-Reviewed Source

Original research published by Posthuma‐Trumpie et al. in Analytical and Bioanalytical Chemistry. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.

Abstract

Lateral flow (immuno)assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats, applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis with lateral flow (immuno)assays using a literature survey and a SWOT analysis (acronym for "strengths, weaknesses, opportunities, threats"). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers. Search terms included "immunochromatography", "sol particle immunoassay", "lateral flow immunoassay" and "dipstick assay".

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Article Details
DOI10.1007/s00216-008-2287-2
JournalAnalytical and Bioanalytical Chemistry
Year2008
AuthorsGeertruida A. Posthuma‐Trumpie, Jakob Korf, A. van Amerongen
LicenseOpen Access — see publisher for license terms
Citations1,506