Prolonged Stimulation of Growth Hormone (GH) and Insulin-Like Growth Factor I Secretion by CJC-1295, a Long-Acting Analog of GH-Releasing Hormone, in Healthy Adults
Sam L. Teichman, Ann Neale, Betty Lawrence et al.
Research Article — Peer-Reviewed Source
Original research published by Teichman et al. in The Journal of Clinical Endocrinology & Metabolism. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.
Subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-I levels in healthy adults and was safe and relatively well tolerated, particularly at doses of 30 or 60 microg/kg. There was evidence of a cumulative effect after multiple doses. These data support the potential utility of CJC-1295 as a therapeutic agent.
Full text is available at the publisher.
Read at Publisher| DOI | 10.1210/jc.2005-1536 |
| Journal | The Journal of Clinical Endocrinology & Metabolism |
| Year | 2006 |
| Authors | Sam L. Teichman, Ann Neale, Betty Lawrence, Catherine Gagnon, Jean‐Paul Castaigne, Lawrence A. Frohman |
| License | Open Access — see publisher for license terms |
| Citations | 35 |