Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog
Madalina Ionescu, Lawrence A. Frohman
Research Article — Peer-Reviewed Source
Original research published by Ionescu et al. in The Journal of Clinical Endocrinology & Metabolism. Redistributed under Open Access — see publisher for license terms. MedTech Research Group provides these references for informational purposes. We do not conduct original research. All studies are the work of their respective authors and institutions.
CJC-1295 increased trough and mean GH secretion and IGF-I production with preserved GH pulsatility. The marked enhancement of trough GH levels by continuous GHRH stimulation implicates the importance of this effect on increasing IGF-I. Long-acting GHRH preparations may have clinical utility in patients with intact pituitary GH secretory capability.
Full text is available at the publisher.
Read at Publisher| DOI | 10.1210/jc.2006-1702 |
| Journal | The Journal of Clinical Endocrinology & Metabolism |
| Year | 2006 |
| Authors | Madalina Ionescu, Lawrence A. Frohman |
| License | Open Access — see publisher for license terms |
| Citations | 34 |